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Olive Leaf Extract: More Than Blood Pressure & Antioxidants

I tested its impact on male hormones, metabolism, and performance.

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Hans
Aug 28, 2025
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Most people think of olive oil as the healthy part of the Mediterranean diet. But almost no one talks about the leaves — and that’s where things get interesting.

Over the past 2 weeks, I’ve been running an experiment with olive leaf extract (320mg oleuropein per day), pushing it beyond the usual “blood pressure and immune health” claims. I tracked it with bloodwork, logged how I felt, and went deep into the research.

The results surprised me. There’s much more happening here than what’s written on a supplement label.

In this article, I’ll show you exactly what I found — from the science, to my own labs, to how it actually felt when I put it to the test.

Here’s what I’ll be discussing:

  • Testosterone & Androgen Support
    How olive leaf extract (OLE) stimulates LH and testosterone via adrenergic pathways.

  • Estrogen & Aromatase Control
    Natural aromatase inhibition and how OLE balances the T:E2 ratio.

  • Cortisol, Stress & Mood Resilience
    The dual effect of OLE on cortisol and its role in stress recovery.

  • Thyroid & Metabolism
    Boosting T3 through adrenergic activation and DIO2 upregulation.

  • Weight Loss & Fat Distribution
    UCP1, PPARα, and how OLE reduces fat pads and improves lipid metabolism.

  • Blood Flow & Erections
    Vasorelaxation, nitric oxide, and endothelial support for better circulation.

  • Gut Health & Endotoxin Blockade
    How OLE protects the gut barrier, blocks LPS, and supports microbiome balance.

  • My experience with lab work
    I put all the in vitro and animal science to the test to see if it really works the same in humans (or just me for that sake).

  • Practical Guide to Using OLE
    Best forms, doses, timing, and synergistic stacks.

  • DIY Shortcut: Making Aglycone at Home
    Step-by-step method to boost absorption with the enzyme shortcut.

  • Caveats & Nuance
    Hormonal paradoxes, dose-dependent effects, and why context matters.

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