Lowering histamine for better sleep: Sleep maxxing (part 2)
Tired but Wired? It’s Probably Histamine (Not Just Stress)
The Histamine–Insomnia Connection You’ve Probably Missed
When most people hear “histamine,” they think allergies: runny nose, itchy skin, maybe a few hives. Pop a Claritin and move on.
But histamine does way more than trigger sneezes.
It’s also a neurotransmitter that keeps you alert.
In fact, histamine is one of the main chemicals your brain uses to stay awake, aroused, and reactive.
And that’s where things start to go wrong…
If histamine gets too high—or isn’t broken down efficiently—you end up with more than just allergies. You get:
Insomnia
Restlessness
Bloating
Irritability
Inflammatory skin issues
Hair loss
Racing thoughts
Racing heart
… and that frustrating feeling of being tired but wired at night.
This is especially common if you’ve already improved your sleep routine, dialed in your melatonin, and you’re still not waking up rested.
In this article, we’ll break down:
What histamine really does in the brain and body
What causes it to build up
How to fix it naturally by targeting mast cells, gut health, and methylation
And when it’s okay to use antihistamines as a short-term tool
Let’s start with what histamine is really doing in your system.