Biohacking got it backwards

You’re trying to upgrade the top while the base is collapsing

You think you need a higher leverage strategy.

Something that moves the needle faster.

Because your goal isn’t small.

You want:

• to age slower

• to look sharper

• to build muscle faster

• to have stable energy

• to have sexual function that actually works

So you look for leverage.

And you land on:

• sauna

• infrared

• hyperbaric oxygen

• NAD & glutathione IV injection

• peptides

• stem cells

Because the belief is:

“If I find the highest leverage input, everything else will follow.”

That belief is why you’re stuck.

The version of you chasing leverage can’t succeed

Try to find the highest leverage levers aren’t wrong. But focus on the least effective ones is.

And it’s because we’ve been led to believe that only the extreme stuff works. The basics are too boring.

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We’re led to believe that true, superior, Gigachad results come from:

→ adding stronger inputs

But your body runs on:

→ constraints

What really matters

Your results are limited by the weakest process (bottleneck), not the strongest input.

You can stack:

• peptides

• supplements

• protocols

But if one process is failing…everything above it gets bottlenecked.

Example:

You eat a “perfect” diet.

But digestion is impaired.

What happens?

• stomach acid is low → protein isn’t broken down

• pancreatic enzymes are insufficient → carbs and fats aren’t processed

• gut lining is inflamed → absorption drops

Now nutrients don’t enter the system properly.

Mechanism → Translation → Consequence

Low digestion → nutrients stay in the gut → bacteria ferment them → endotoxin (lipopolysaccharide) increases.

Endotoxin binds TLR4 receptors → activates NF-κB → increases inflammation.

That inflammation:

• reduces mitochondrial efficiency

• impairs hormone signaling

• drains energy

• speeds up aging

Translation:
You eat clean and healthy, but your body can’t use it.

Consequence:
Adding more “high leverage” inputs does nothing.

Absorption sets the ceiling.

Same with endotoxin.

If the gut is inflamed:

• bacteria produce endotoxin

• endotoxin enters circulation

• immune system stays activated

This isn’t sporadic, once in a blue moon.

It’s constant.

Mechanism → Translation → Consequence

Endotoxin activates TLR4 → increases inflammatory signaling → interferes with mitochondrial respiration

Translation:
Your cells can’t produce energy efficiently.

Consequence:
You feel tired, unmotivated, flat, achy. Old.

And you try to fix it with more inputs.

You don’t need more energy production.
You need less energy being stolen.

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Same with your nervous system.

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If you breathe fast and shallow all day:

• CO2 drops

• oxygen delivery becomes less efficient (Bohr effect)

• sympathetic tone stays high

So your body stays in a stress state which leads to poor sleep, poor recovery, poor performance.

And then you try to “recover harder” with peptides, red light, hyperbaric chamber, TRT, etc.

Not that those are bad, but they don’t address the bottlenecks.

Not to be a hypocrite: those tools are amazing and I do recommend some of them when appropriate, but always in conjunction with a protocol that address the bottlenecks as well.

This is the real mistake

You are trying to override constraints instead of removing them.

Even the people who are supposed to understand this… don’t.

They just make the same mistake at a higher level.

If they don’t have money:

They use:

• resveratrol

• NAD boosters

• SIRT1 activators

• Telomere lengthening agents

If they do have money:

They upgrade to:

• ice baths

• infrared saunas

• hyperbaric oxygen

• stem cells

Different tools…but same model.

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They’re all trying to hack the top of the system.

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Very few focus on:

• nutrient density

• digestion

• gut integrity

• endotoxin load

Which are the processes that determine whether anything else works.

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There are exceptions.

Chris Masterjohn is one of them.

He focuses almost entirely on:

• micronutrients

• deficiencies

• biochemical sufficiency

And it’s working amazingly well.

Using one of the most advanced (best) biological aging metrics available (DunedinPACE), he’s ranking #6. Which is six places ahead of Bryan Johnson and 19 places ahead of Peter Diamandis of X-Prize fame.

I am aging at only 2/3 the normal rate!

And those are people spending millions on advanced interventions.

And he’s outperforming them by focusing on nutrients.

Yes, this is early data and the sample is still small, but the pattern is hard to ignore.

The foundation matters more than the tools built on top of it.

Now there’s a deeper layer.

The comfort trap

You think your choices are rational.

They’re not.

They’re environmental.

If warm water exists…

You take warm showers.

If couches exist…

You sit.

If hyper-palatable food exists…

You eat more.

Not because it’s optimal.

Because it’s available.

Now remove the option.

No warm water.

You take cold showers.

At first it’s uncomfortable.

Then:

• catecholamines increase

• alertness increases

• mood improves

What was uncomfortable becomes rewarding, and even enjoyable.

Your preferences are trained by your environment.

This is why discipline fails.

You’re trying to override an environment that makes the wrong choice easy.

Here’s an easy way to thinking about discipline

Discipline is not doing hard things.

It is removing the easy wrong ones.

A common example is just not to have cookies in the house. A simple solution to prevent buying takeout all the time is to have already prepared food at home/work waiting for you when the hunger pangs kick in.

That makes discipline close to absolute.

Why your past attempts failed

You tried to:

• stack high leverage interventions

• ignore foundational constraints

• maintain discipline in a comfort-heavy environment

That combination always breaks.

Most people skip the basics because they don’t feel like leverage.
But the basics are the only things that compound.

“Pfff, you’re telling me eating steak, liver, oysters, eggs, dairy and easy-to-digest carbs will improve my symptoms?” Damn right!

Think about it this way

Stop asking:

“What’s the highest leverage thing I can add?”

Start asking:

“What is currently limiting everything else?”

Because:

• digestion sets absorption

• absorption sets nutrient status

• nutrient status sets cellular function

• cellular function sets energy, hormones, performance

Not the other way around.

The highest leverage intervention is not the most advanced.
It’s the one removing your biggest constraint.

And most people never look there, because it’s too simple to feel powerful.

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If you want to know what’s actually limiting your progress, I can map it out for you.

Most people don’t need more inputs.
They need to identify the bottleneck that’s making everything else underperform.

That’s exactly what I do in the health report.